The success of the symposium in 2005 encouraged the leadership of the ISCB Student Council to organize a very similar event as part of ISMB 2006 in Fortaleza, Brazil. Even though the symposium was held on the same day as the tutorials of ISMB over 80 delegates registered for this event, which had a strong focus on career-development and networking within the bioinformatics community. Keynote speakers Phil Bourne, Reinhard Schneider and Julio Collado-Vides dedicated time to these issues in their keynote presentations, while then-ISCB President Michael Gribskov discussed his vision of where computational biology is heading in the 21st century in his closing remarks.

Many students and young researchers used the opportunity to present their work at the event and submitted more than 35 abstracts. The best 10 were selected for oral presentation, while a poster session allowed also the remaining submitters to present their work. Awards were given to the authors of the best presentation and the best poster. The day was closed by a social event in one of Fortaleza's best steakhouses, which was another highlight of this very successful 2nd ISCB Student Council Symposium.